Resurrecting Plant Immunity With Large-Scale Protein Engineering

Resurrecting Plant Immunity With Large-Scale Protein Engineering

Bacteria, oomycetes, and other pathogens extract a heavy toll on the farming community. Together, they’re responsible for a near 20% reduction in global crop production each year. Farmers have long sought to identify and breed resistant crop strains, but doing so can be an arduous task that spans more than a decade. Resurrect Bio is seeking to change this, enabling farmers to hone resistant pathogen resistance in just a single year. Using a combination of AI, DNA synthesis, and a rapid in planta screening platform, Resurrect Bio identifies and screens tens of thousands of protein-protein interactions to identify how pathogens suppress plant immune systems. Through precise genome engineering, the team can then resurrect plant immunity, giving farmers a unique leg up in the eternal fight against pests.

Covered in this Case Study

  • How plant pathogens suppress immunity
  • How AI is helping Resurrect Bio both identify and disrupt these key pathogen-host interactions
  • How Twist’s ability to synthesize custom, AI-designed gene fragments enables the Resurrect team to overcome a common AI bottleneck, ultimately to resurrect plant immunity.

Share your details to Get the Case Study

Related Resources