Accelerated, Function forward Therapeutic Antibody Discovery Targeting an Intractable Cell Surface Receptor

Accelerated, Function forward Therapeutic Antibody Discovery Targeting an Intractable Cell Surface Receptor

Covered in this Case Study

  • Use of different antigens produced target-specific titer responses in both DiversimAb and humanized mice
  • High resolution screening of entire plasma cell population in one single day
  • NGS repertoire clonotype analysis of various mice led to opportunities to identify additional hits from repertoire sequences

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